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Fig. 2 | BMC Genomics

Fig. 2

From: Modifier locus mapping of a transgenic F2 mouse population identifies CCDC115 as a novel aggressive prostate cancer modifier gene in humans

Fig. 2

Summary of phenotypic data collected from n = 307 (TRAMP x WSB) F2 transgene positive mice. At 210 days, or when human end points were reached, mice were scarified and tissues collected and analyzed for primary tumor burden and distant metastases. a Age of death. b Prostate tumor burden. c Seminal vesicle tumor burden. d Visceral and lymph node metastasis (Incidence %). Representative H&E staining. e Lung. f Liver. g Lymph node

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