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Fig. 5 | BMC Genomics

Fig. 5

From: Modifier locus mapping of a transgenic F2 mouse population identifies CCDC115 as a novel aggressive prostate cancer modifier gene in humans

Fig. 5

Lentiviral ectopic over-expression of candidate genes CCDC115, DNAJC10, RNF149 and STYXL1 in the LNCaP PC cell line and their functional effect in vitro and in vivo. a Cell proliferation rates. b Anchorage independent growth. c Invasion. d Flank xenograft tumor growth over time. e Final tumor weight after 5 weeks growth. *p < 0.05; ** p < 0.01; ***p < 0.001

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