Skip to main content

Table 1 Significant aggressive PC susceptibility modifier loci in (TRAMP x WSB) F2 mice

From: Modifier locus mapping of a transgenic F2 mouse population identifies CCDC115 as a novel aggressive prostate cancer modifier gene in humans

Trait

Chromosome

LOD Score

P-Value

2-LOD Confidence Interval

Proximal (bp)

Distal (bp)

Primary Tumor Burden

1

4.96

0.004

16,278,642

64,873,174

2

4.13

0.026

44,988,302

107,465,137

5

4.22

0.023

129,258,884

139,764,653

13

6.92

< 0.001

60,718,040

98,858,290

18

4.28

0.02

73,432,362

88,633,996

Seminal Vesicle Tumor Burden

4

13.77

< 0.001

3,722,677

46,175,356

  1. bp base pair