Skip to main content

Table 1 Significant aggressive PC susceptibility modifier loci in (TRAMP x WSB) F2 mice

From: Modifier locus mapping of a transgenic F2 mouse population identifies CCDC115 as a novel aggressive prostate cancer modifier gene in humans

Trait Chromosome LOD Score P-Value 2-LOD Confidence Interval
Proximal (bp) Distal (bp)
Primary Tumor Burden 1 4.96 0.004 16,278,642 64,873,174
2 4.13 0.026 44,988,302 107,465,137
5 4.22 0.023 129,258,884 139,764,653
13 6.92 < 0.001 60,718,040 98,858,290
18 4.28 0.02 73,432,362 88,633,996
Seminal Vesicle Tumor Burden 4 13.77 < 0.001 3,722,677 46,175,356
  1. bp base pair