Fig. 3

Genome-wide significant (P < 1e-11) eCpG-transcript relationship proportions in GTP (inner; n = 2466) and MESA (outer; n = 34,518). The green sections represent eCpGs that are < 50 kb from their associated transcript (cis); yellow represents eCpGs that fall within the gene body of their associated transcript; dark blue represents eCpGs that were < 50 kb, but on the same chromosome (distal) as the associated transcript; and light blue represents eCpGs that were on a different chromosome from the associated transcript (trans). Definitions of each category are given in Fig. 4 and Materials and Methods section