Chromosome | Cosmid identifier | Gene | Brief description |
---|---|---|---|
I | ZC123.3 | Homeobox protein; homologue to human ATBF1 transcription factor and tumour suppressor | |
I | Y110A7A.10a | aap-1 | PI3K p50/55 adaptor/regulatory subunit orthologue |
I | T08B2.10 | rps-17 | 40S ribosomal protein S17 |
I | F57B10.8 | Activator of basal transcription | |
I | F26E4.4a | Activator of basal transcription | |
I | T06G6.9a | pfd-3 | Molecular chaperon Prefoldin, subunit 3; orthologue to human VHL-binding protein tumour suppressor |
I | Y87G2A.ha | gpi-1 | Putative glucose 6-phosphate isomerase; Required for normally short lifespan |
II | C23H3.4a | sptl-1 | Putative serine palmitoyltransferase |
II | F53A10.2 | Rap-1 GTPase-activating protein; orthologue to a human tumour suppressor in squamous cell carcinoma | |
II | T05C1.6a | Calmodulin-binding transcriptional activator | |
II | R07G3.1 | cdc-42 | RHO small GTPase; regulator of polarity |
II | T05C12.6 | mig-5 | One of three homologues to Dishevelled in Drosophila |
II | T22C8.2 | chhy-1 | Chondroitin hydrolase; similar to human HYAL1, a potential tumour suppressor in lung cancer cell lines |
II | F40F8.9a | lsm-1 | Small nuclear ribonucleoprotein splicing factor |
II | T06D8.2a | No description available | |
II | C50E10.3a | sre-53 | G protein-coupled chemoreceptor |
II | W01D2.2 | nhr-61 | Nuclear hormone receptor |
III | R74.2a | No description available | |
III | Y44F5A.1 | Protein containing WD40 repeats; required for protein-protein interactions | |
III | C27F2.4a | Predicted protein carboxyl methylase | |
III | R02F2.7a | No description available | |
III | F54E7.3 | par-3 | PDZ-domain containing protein; required for polarization of the early embryo |
III | B0336.3a | Protein containing and RNA recognition motif | |
III | C07H6.5 | cgh-1 | Putative RNA helicase; inhibits apoptosis in oocytes |
III | C50C3.9a | unc-36 | Voltage-dependent calcium ion channe |
III | Y52D3.1 | strd-1 | Activator of LKB1 |
IV | F15E6.8 | dct-7 | RNA binding protein controlled by DAF-16/FOXO; affects germline tumours |
IV | H35B03.2a | Subunit of nuclear ribonuclease P | |
IV | C06E7.1a | sams-3 | S-adenosylmethionine synthetase |
IV | F12F6.5 | sgrp-1 | Homologue to Cdc42-interacting protein CIP4 |
IV | Y51H4A.c | rho-1 | Rho GTPase; required for actin filament-based processes including embryonic polarity |
V | F48G7.9 | Serine/threonine protein kinase | |
V | C39F7.4 | rab-1 | Ras-like GTPase, orthologue to Rab1 |
V | T03D3.11a | srj-44 | 7-transmembrane olfactory receptor |
V | F26D11.11a | let-413 | Localizes to basolateral region of epithelial cells and required for adherens junction formation; strong homology to Drosophila Scribble |
X | C14A11.3 | cgef-1 | Guanosine nucleotide exchange factor for Rho and Rac GTPases |
X | C38C5.1a | No description available | |
X | F13B9.5 | ksr-1 | Kinase suppressor of Ras |
X | T09B9.3a | Glycerophosphoryl diester phosphodiesterase |