Fig. 2
From: LPG: A four-group probabilistic approach to leveraging pleiotropy in genome-wide association studies
The comparison of LPG (VB joint) and its alternative methods, BVSR (VB separate) and Lasso, for binary traits demonstrated increased power in ascending order of pleiotropy g, while the FDR of both LPG and BVSR were controlled at 0.2. Panels from top to bottom are the AUC, FDR, Power and Prediction. Choices of g range from 0 to 1. The parameter settings of the model are : p = 20,000, n1=n2 = 3000, h2 = 0.5, ρ=0.5 and α1 = 0.0025