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Table 3 Inference of pleiotropy

From: LPG: A four-group probabilistic approach to leveraging pleiotropy in genome-wide association studies

 

LRT

p-value

CD-T1D-inMHC

2.27e-05

1

RA-T1D-inMHC

1.03e+02

2.75e-24

T1D-CD-inMHC

-8.87e-02

1

T1D-RA-inMHC

7.25e+01

1.68e-17

CD-T1D-exMHC

8.22e+00

4.13e-03

RA-T1D-exMHC

2.33e+01

1.38e-06

T1D-CD-exMHC

4.73e+00

2.96e-02

T1D-RA-exMHC

2.07e+01

5.29e-06

  1. Pleiotropy estimated and inference, inMHC means including the MHC region and exMHC means excluding the MHC region