Fig. 3

Gene Ontology (GO) functional classification network. All significant genes (human Entrez Gene IDs) in three cell types were used as input for the ToppCluster. The following databases were used, i.e. “biological process”, “cellular component”, “molecular function” and pathway. Finally, the data were uploaded in Cytoscape 3.4.0 to modify the network. Nodes were colored based on specificity: red nodes specific for luminal epithelium (LE), glandular epithelium (GE), and stromal cells (S); nodes for the three GO functions and pathway were in different colors