Fig. 2
Regional association plots for five novel loci across a 1-Mb window. Association of individual SNPs in the discovery GWAS plotted as −log10(P) against the chromosomal base-pair position. The y-axis on the right shows the recombination rate, estimated from the HapMap CHB and JPT populations. P-values are from the discovery phase. The purple circle and diamond represent the results of discovery and meta-analysis (Phase 1 + 2), respectively. Seven signal plots for five novel SNPs are illustrated, which show the genome-wide significant P-values in the meta-analysis (Phase 1 + 2). a rs7567283 of the right facial angle of en-ex-go [(A) enR-exR-goR], b rs970797 of the tangent line angle of er3 [(A) Tan_er3], c rs970797 of the tangent line angle of el3 [(A) Tan_el3], d rs3736712 of eye tail length (psR-exR), e rs2193054 of profile nasal angle [(A) n-prn-sn], f rs2193054 of nasal tip protrusion [(H) prn-sn], and g rs2206437 of subnasal width (sbalR-sbalL)