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Table 2 Association test between the three eQTL hotspots that harbor TF in their region, and IMF content traits

From: Identification of putative regulatory regions and transcription factors associated with intramuscular fat content traits

eQTL hotspots

rs135914685- hotspot 1(USF1)

rs110242967 - hotspot 2 (EGR4)

rs134095631 - hotspot 3 (RUNX1T1)

Traits

p-value

FDR1

p-value

FDR

p-value

FDR

BFTa

1.89E-06

7.47E-06i

2.77E-06

8.30E-06i

8.30E-06

2.07E-05i

IMFb(%)

3.55E-02

6.61E-02

7.61E-02

8.15E-02

3.24E-02

3.74E-02i

Myristic (%)

5.45E-04

2.30E-03i

1.51E-05

2.84E-05i

1.40E-05

2.63E-05i

Myristoleic (%)

2.73E-05

1.14E-04i

3.61E-04

5.41E-04i

5.65E-04

7.71E-04i

Palmitic (%)

5.37E-07

7.47E-06i

5.34E-07

2.00E-06i

5.55E-07

2.08E-06i

Palmitoleic (%)

1.21E-05

5.45E-05i

9.73E-06

2.09E-05i

1.20E-05

2.58E-05i

Stearic (%)

1.38E-01

1.89E-01

1.21E-01

1.21E-01

1.61E-01

1.61E-01

Oleic (%)

2.04E-14

5.17E-13i

2.11E-14

1.06E-13i

1.76E-14

8.82E-14i

Linoleic (%)

2.74E-02

4.27E-02i

3.65E-02

4.21E-02i

4.22E-02

4.53E-02i

CLAc9t11c(%)

2.20E-16

3.30E-15i

2.20E-16

3.30E-15i

2.20E-16

3.30E-15i

SFAd(%)

4.78E-06

3.75E-05i

4.62E-06

1.16E-05i

4.09E-06

1.23E-05i

MUFAe(%)

1.72E-05

8.81E-05i

1.66E-04

2.76E-04i

1.41E-04

2.35E-04i

PUFAf(%)

3.09E-04

1.26E-03i

4.03E-04

5.49E-04i

4.03E-04

6.04E-04i

Sum_n3g(%)

2.20E-16

3.30E-15i

2.20E-16

1.65E-15i

2.20E-16

1.65E-15i

Sum_n6h(%)

1.24E-02

3.80E-02i

1.10E-02

1.38E-02i

9.68E-03

1.21E-02i

  1. aBackfat thickness
  2. bintramuscular fat
  3. cconjugated linoleic acid cis9 trans11
  4. dsaturated fatty acid
  5. emonounsaturated fatty acid
  6. fpolyunsaturated fatty acid
  7. gsum of omega-3, and
  8. hsum of omega-6
  9. iSignificant FDR 5%
  10. 1FDR – Adjusted p-value using the false discovery rate method by Benjamini and Hochberg 1995