Transferring knowledge of bacterial protein interaction networks to predict pathogen targeted human genes and immune signaling pathways: a case study on M. tuberculosis

Table 2 GO enrichment analysis of the derived interlog {Rv2737c, ERCC6}. recA (Rv2737c) is classified into the drug resistance type of SOS-response and DNA replication that leads to mutations in the gene or its regulatory region [46]

	GO term ID	GO aspect	GO term name
Common GO terms	GO:0005515	F	protein binding
	GO:0006281	P	DNA repair
	GO:0006974	P	response to DNA damage stimulus
	GO:0016787	F	hydrolase activity
	GO:0008094	F	DNA-dependent ATPase activity
	GO:0003677	F	DNA binding
recA\|Rv2737c only	GO:0046677	P	response to antibiotic
	GO:0009432	P	SOS response
	GO:0009650	P	UV protection
	GO:0010212	P	response to ionizing radiation
	GO:0006310	P	DNA recombination
	GO:0006259	P	DNA metabolic process
	GO:0000725	P	recombinational repair
ERCC6 only	GO:0000303	P	response to superoxide
	GO:0006283	P	transcription-coupled nucleotide-excision repair
	GO:0006284	P	base-excision repair
	GO:0006979	P	response to oxidative stress
	GO:0007256	P	activation of JNKK activity
	GO:0008630	P	DNA damage response, signal transduction resulting in induction of apoptosis
	GO:0010332	P	response to gamma radiation
	GO:0009411	P	response to UV

C denotes cellular component, F denotes molecular function, and P denotes biological process

ISSN: 1471-2164