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Table 3 Performance estimation of 5-fold cross validation and performance comparison with the existing methods

From: Transferring knowledge of bacterial protein interaction networks to predict pathogen targeted human genes and immune signaling pathways: a case study on M. tuberculosis

  Size Combined-instance Homolog-instance Target-instance
SP SE MCC SP SE MCC SP SE MCC
Positive 15,287 0.9823 0.9966 0.9790 0.9684 0.9915 0.9601 0.9820 0.9976 0.9796
Negative 15,287 0.9965 0.9821 0.9790 0.9912 0.9676 0.9601 0.9975 0.9817 0.9796
[Acc; MCC] [98.93%; 0.9789] [97.95%; 0.9599] [97.95%; 0.9599]
[ROC-AUC] [0.9933] [0.9912] [0.9978]
F1 Score 0.9894 0.9798 0.9897
KMM-SVM [23] SP SE F1 score
human- > mouse 0.517 0.937 0.667
E.coli- > human 0.257 0.161 0.199
  1. denotes the work [23] that transfers the knowledge of Salmonella-human PPI networks to predict Salmonella-mouse protein interactions; denotes the work [23] that transfers the knowledge of Salmonella-Ecoli PPI networks to predict Salmonella-human protein interactions