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Fig. 2 | BMC Genomics

Fig. 2

From: Genome data uncover four synergistic key regulators for extremely small body size in horses

Fig. 2

Genotype distribution of height associated variants. The withers height of the investigated Shetland ponies and related breeds is compared with the variant genotypes of ADAMTS17, OSTN, GH1 and HMGA2 (a). General linear model analysis confirmed a significant association of variant genotypes with height at the withers. A considerably lower withers height can be seen in ponies with a homozygous mutant genotype for all four variants. Comparative evaluation of all four genotypes shows a powerful synergistic effect (b). None of the horses with homozygous mutant genotypes of all variants or homozygous mutant genotypes of three variants plus a heterozygous genotype of the fourth variant shows a withers height higher than 87 cm

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