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Table 1 Top positively Shh-regulated concordant genes

From: Identification of sonic hedgehog-regulated genes and biological processes in the cranial neural crest mesenchyme by comparative transcriptomics

Rank

Gene Symbol

In vitro FC (SHH/Veh)

In vitro FDR p-value

In vivo FC (Veh/Cyc)

In vivo FDR p-value

1

Gli1

25.62

0.000009

1.61

0.104969

2

Hhip

114.91

0.000001

1.56

0.119514

3

Ptch2

8.68

0.000009

1.55

0.006306

4

Ptch1

21

8.20E-07

1.47

0.007005

5

Gm5127

7.49

0.000117

1.48

0.538991

6

Foxd1

6.37

0.000056

1.44

0.380027

7

Foxf2

2.43

0.000041

1.83

0.175736

8

Id4

2.13

0.000259

1.55

0.723333

9

Epha3

3.7

0.00002

1.31

0.668124

10

Frem1

4.18

0.000039

1.21

0.442643

11

1700018A04Rik

5.58

0.000086

1.19

0.698151

12

Adamts15

6.61

0.000038

1.17

0.704734

13

Lama2

3.76

0.00002

1.19

0.571271

14

Lypd6

11.4

0.000125

1.12

0.737329

15

Trp53i11

2.57

0.000119

1.22

0.516635

16

St8sia2

6.19

0.000014

1.15

0.488058

17

Arhgap20

2

0.004416

1.24

0.529114

18

Gm13476

3.2

0.000017

1.18

0.641684

19

Ntn1

3.23

0.000133

1.11

0.618111

20

Ckb

1.19

0.000728

1.5

0.447282

21

Fez1

1.66

0.00097

1.19

0.704734

22

Gpr30

1.76

0.000049

1.15

0.704734

23

Foxc2

1.28

0.004471

1.34

0.442166

24

H2-Ke6

1.69

0.001836

1.12

0.516635

25

Ephb2

2.79

0.000911

1.08

0.73884

26

Adam5

1.53

0.009818

1.13

0.704734

27

Efnb1

1.67

0.000085

1.11

0.618111

28

Rfc3

1.51

0.000725

1.14

0.41917

29

Fgfr2

1.67

0.000309

1.11

0.689333

30

Nek7

1.17

0.003294

1.18

0.618111

  1. FC fold change
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