Refining a steroidogenic model: an analysis of RNA-seq datasets from insect prothoracic glands

BMC Genomics

Table 1 Tabulation of expression and phenotypic data of Drosophila melanogaster and Bombyx mori genes that are orthologous to human genes encoding proteins that comprise the transduceosome [13, 34]

Bombyx mori gene ID	Flybase gene ID	FPKM Prothoracic gland	FPKM Ring gland	Phenotype	Orthologue of	Proteome Discoverer®1.4 -assigned score
–	–	–	–	–	ACOT2/3	–
BMgn002906	FBgn0031992	325,15	252,53	NOP	ACBD1(DBI)	9
BMgn003788	FBgn0263120	43,36	98,55	NOP	ACSL4	32.7
BMgn003829	FBgn0003360	0^a	734,65	major delay	ANT	136.2
BMgn003985	FBgn0261014	146,4	524,02	major delay	ATAD3	179.5
BMgn004096	FBgn0022382	21,3	43,05	NOP	PKA-R2	45.6
BMgn006907	FBgn0001248	280,84	423,08	major delay	IDH2	52.5
BMgn007194	FBgn0036892	17,71	36,2	NOP	LONP1	68.7
BMgn007586	FBgn0001248	15,67	423,08	major delay	IDH2	47.6
BMgn008137	FBgn0011769	10,88	12,93	L3 arrest	FDX1	4.7
BMgn008154	FBgn0261276	18,37	45,42	NOP	OPA1	34.8
BMgn008523	FBgn0023536	15,08	15,56	NOP	ACBD3 (PAP7)	12
BMgn008955	FBgn0004363	0^a	470,55	NOP	VDAC	128.8
BMgn009790	FBgn0035028	6,72	2276,69	NOP	MLN64/StARD1 (START1)	–
BMgn011029	FBgn0029969	320,13	101,65	NOP	ACAT1	130.1
BMgn011694	FBgn0259243	21,61	33,49	NOP	PKA-R1	–
BMgn012659	FBgn0040064	156,94	279,4	NOP	ACAT1	115.7
BMgn013063	FBgn0262559	121,72	270,08	NOP	MDH2	101
BMgn017207	FBgn0010926	126,01	12,43	L3 arrest	TSPO	-^b
BMgn017400	FBgn0035529	73,26	85,12	L1, L2, L3 arrest	FDX2	−^b
BMgn017553	FBgn0015582	57,92	31,17	L3 arrest	FDXR (Dare)	-^b

Data from the proteomic analysis of V-6 PGs of Bm using Proteome Discoverer®1.4 is derived from [28]. Data from phenotypic analysis of RG-specific RNAi-mediated gene knockdown is derived from [32]. See Additional file 9: Table S8 for details
^aFragments > 1,000,000
^bNo Uniprot record

ISSN: 1471-2164