Fig. 5

Shared genetic influence on the splicing, exon and gene expression between tissues. Blood refers to white blood cells and milk refers to milk cells. a Each matrix shows the pair wise comparison of the numbers of significant SNP and the total number of significant SNPs detected for each analysis shown in parentheses. The significance of each overlap was tested by Fisher’ exact test, given the total number of SNP analysed and the total number of significant SNP, the result of which is represented by the colour of that position in the matrix. b Each matrix shows the pair wise comparison of the numbers of exon/gene with significant associations and the total number of exon/gene detected with significant associations for each analysis shown in parentheses. In panel (b), the numbers were either exon numbers for sQTLs (splicing quantitative trait loci) and eeQTLs (exon expression quantitative trait loci) or gene numbers for geQTLs (gene expression quantitative trait loci. c Between tissue genetic correlations of either the inclusion ratio of the exons, the expression of the exons or the expression of the genes that had significant sharing of expression QTLs in panel (a). Dot size and transparency were negatively correlated with p value of the significance of the genetic correlation being different from 0. The error bars of the genetic correlation were shown in vertical lines of each dot. Some genes of interests were highlighted