Fig. 3
From: Recurrent tumor-specific regulation of alternative polyadenylation of cancer-related genes
Selected events of tumor-specific APA regulations that do not fit the 3’ UTR length modulation paradigm. (a,b) CDKN2A in KIRC and HNSC. (c) EZH2 in LUAD. (d) PTCH1 in BRCA. (a-d) The legend of Fig. 2 applies. In addition, when the 3’ UTR length change is too complex to be resolved into a shortening or lengthening trend, the corresponding text box is left uncolored. NMD-related transcript elements are colored in cyan. An orange arrow indicates that a predicted CS with a significant frequency change is mapped to multiple stop codons, with its associated 3’ UTR length being ambiguous. A high-resolution version of this figure is available for download in Additional file 5