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Table 1 Individual genes in the TGF-β and WNT pathways that demonstrated an association with colorectal cancer

From: Stepwise approach to SNP-set analysis illustrated with the Metabochip and colorectal cancer in Japanese Americans of the Multiethnic Cohort

Gene

No. SNPs

Pathway

P value

All CRC

Colon cancer only

WNT11

1

WNT

0.0064

0.014

TGFBR2

78

TGF-β

0.0075

0.15

SMAD7

6

TGF-β and WNT

0.015

0.058

TCF7L2

26

WNT

0.019

0.045

TFDP1

1

TGF-β

0.044

0.040