Fig. 5From: Characterization of kinase gene expression and splicing profile in prostate cancer with RNA-Seq dataA hypothetic model of the function of CDK5 isoform switching in prostate cancer. The dominance of Isoform1 over Isoform2 in cancer increases the phosphorylation of AR, which increases its protein stabilization and activity in nucleus, and thus promote cancer-related cellular process like cell proliferationBack to article page