Fig. 2

Evolutionary relationships for the polyproteins of the ZIKV and DENV types. a A neighbor-joining tree likelihood of distance between the minInDel patterns of ZIKV and DENV types. b A topology of the maximum likelihood tree based on a gapless multiple sequence alignment of the full polyprotein sequences of the ZIKV and DENV strains. c A topology of a minimum evolution tree with a distance correction by calculating the minInDel frequencies in the polyprotein sequences. Virus types and hosts are differentiated by different colours of triangles and circles shown at the front and end of each strain code, and four cases of microcephaly are indicated by asterisks. The neighbor-joining trees with branch lengths are shown in Additional file 3. d The 10-year average genetic distance plots of the African and Asian strains that belong to ZIKV type II