Analysis of codon usage patterns in Hirudinaria manillensis reveals a preference for GC-ending codons caused by dominant selection constraints

Table 1 Relative synonymous codon usage (RSCU) values of coding sequences (CDSs) in Hirudinaria manillensis

AA	Codon	RSCU	AA	Codon	RSCU	AA	Codon	RSCU	AA	Codon	RSCU
Ala	GCU	1.06	His	CAC	1.111	Pro	CCA	1.16	Ser	UCG	0.907
	GCG	0.438		CAU	0.889		CCC	0.883		UCU	1.062
	GCC	1.39	Ile	AUU	1.074		CCU	1.134	Thr	ACC	1.134
	GCA	1.113		AUA	0.69		CCG	0.823		ACA	0.938
Cys	UGU	0.81		AUC	1.236	Gln	CAA	0.962		ACG	0.895
Cys	UGC	1.19	Lys	AAA	0.981		CAG	1.038		ACU	1.032
Asp	GAU	0.966		AAG	1.019	Arg	AGA	1.025	Val	GUU	1.12
Asp	GAC	1.034	Leu	CUA	0.365		AGG	0.975		GUG	1.029
Glu	GAG	0.837		CUC	1.335		CGA	1.379		GUC	1.409
Glu	GAA	1.163		CUG	1.334		CGC	0.944		GUA	0.442
Phe	UUU	0.915		CUU	0.967		CGG	0.702	Trp	UGG	1
Phe	UUC	1.085		UUA	0.546		CGU	0.975	Tyr	UAC	1.15
Gly	GGU	0.972		UUG	1.454	Ser	AGC	1.061		UAU	0.85
	GGG	0.536	Met	AUG	1		AGU	0.939
	GGC	0.948	Asn	AAC	1.087		UCA	0.957
	GGA	1.544		AAU	0.913		UCC	1.074

Notes: All codons except for stop codons were included in this analysis. AA: amino acids. Codons with RSCU > 1.25 are shown in bold, codons with RSCU < 0.75 are shown with underlined text

ISSN: 1471-2164