Fig. 2
From: eQTL discovery and their association with severe equine asthma in European Warmblood horses
eQTLs. a Linear regression for the effect of genotype (homozygous reference = 0, heterozygous = 1, and homozygous alternative = 2) on gene expression for gene glucosidase alpha (GAA) in treatment MCK1. The line was fitted to all individuals and grey shading is the standard error. Red triangles are cases, and black circles are controls. Density functions surround plot points: black for genotype 0, red for genotype 1, and green for genotype 2. Here, one unit change in genotype is a good predictor for an additive change in gene expression. This eQTL implies that some variant inside the QTL (surrounding the significant SNP) is regulating gene expression. b Histogram showing the frequency of distances between a genes’ transcription start site (TSS) and the eSNP that is associated with that genes’ expression in the HDE treatment