Fig. 4
From: Effects of liquid cultivation on gene expression and phenotype of C. elegans
Different strains and the environment conditions contribute to differences in the maternal gene expression profiles. a The DEGs in the F1, F2, and both (F1F2) generations were identified in comparison to the gene expressions in the P0 animals. Between 5 to 34% of the DEGs in the F1 generations were transmitted to the F2 generations (see the third category – F1F2) and these transmissions are higher than expected by chance (hypergeometric test, P-value < 0.001 for all the upregulated and downregulated genes individually). The gene expressions transmitted to the next generation after exposure to CeHR showed distinct enrichments for sequence motifs in their promoter regions for N2 and AB1 strains. The number of DEGs genes in F1, F2, and F1F2 were represented with blue, green, and purple, respectively. b Top five tissue enrichment of the DEGs under exposure to environmental changes in F1 (FDR-adj. P-value < 0.05)