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Table 1 Comparison of de novo genome assembly methods

From: Nanopore sequencing and full genome de novo assembly of human cytomegalovirus TB40/E reveals clonal diversity and structural variations

  Hybrid Assembly Spades Assembly
Assembly vs. reference statistics
 Genome fraction (%) 98.62 92.54
 Duplication ratio 3.85 1.60
 Genes covered 170 + 0 partial 144 + 24 partial
 Largest alignment 175,612 13,936
 Total aligned length 900,508 350,687
 NG50 230,347 9304
 NG75 230,347 6488
Statistics without reference
 Contigs 37 127
 Largest contig 230,347 17,689
 Total length 985,159 452,509
 N50 41,056 5686
 N75 22,636 3766
 GC (%) 57 57