HLA allele | No. of strong-binding neo-antigens | No. of weak-binding neo-antigens | Total neo-antigens | HLA frequency in Caucasian population | P value | Q value |
---|---|---|---|---|---|---|
DRB1*01:02 | 88 | 1174 | 1262 | 1.40% | 1.57E-24 | 4.86E-23 |
DRB1*12:01 | 98 | 1046 | 1144 | 1.60% | 9.03E-24 | 1.40E-22 |
DRB1*11:04 | 48 | 756 | 804 | 2.90% | 4.04E-23 | 4.18E-22 |
DRB1*01:01 | 54 | 896 | 950 | 8.60% | 1.93E-22 | 1.50E-21 |
DRB1*01:03 | 4 | 392 | 396 | 1.20% | 1.11E-06 | 6.86E-06 |
DRB1*13:03 | 3 | 385 | 388 | 1.10% | 6.80E-05 | 3.51E-04 |
DRB1*16:02 | 22 | 293 | 315 | 0.15% | 2.52E-01 | 1.00E + 00 |
DRB1*03:01 | 4 | 303 | 307 | 12.20% | 4.31E-01 | 1.00E + 00 |
DRB1*11:03 | 2 | 248 | 250 | 0.61% | 9.68E-01 | 1.00E + 00 |
DRB1*08:03 | 3 | 225 | 228 | 0.24% | 1.00E + 00 | 1.00E + 00 |
DRB1*07:01 | 6 | 217 | 223 | 13.40% | 1.00E + 00 | 1.00E + 00 |
DRB1*04:05 | 3 | 217 | 220 | 0.67% | 1.00E + 00 | 1.00E + 00 |
DRB1*04:01 | 2 | 213 | 215 | 8.80% | 1.00E + 00 | 1.00E + 00 |
DRB1*08:04 | 7 | 190 | 197 | 0.20% | 1.00E + 00 | 1.00E + 00 |
DRB1*10:01 | 12 | 179 | 191 | 0.85% | 1.00E + 00 | 1.00E + 00 |
DRB1*09:01 | 4 | 175 | 179 | 1.00% | 1.00E + 00 | 1.00E + 00 |
DRB1*04:04 | 0 | 151 | 151 | 3.90% | 1.00E + 00 | 1.00E + 00 |
DRB1*13:05 | 4 | 137 | 141 | 0.25% | 1.00E + 00 | 1.00E + 00 |
DRB1*13:02 | 0 | 137 | 137 | 4.90% | 1.00E + 00 | 1.00E + 00 |
DRB1*16:01 | 1 | 124 | 125 | 1.40% | 1.00E + 00 | 1.00E + 00 |
DRB1*08:01 | 2 | 121 | 123 | 2.30% | 1.00E + 00 | 1.00E + 00 |
DRB1*11:01 | 4 | 116 | 120 | 5.60% | 1.00E + 00 | 1.00E + 00 |
DRB1*13:01 | 0 | 116 | 116 | 5.60% | 1.00E + 00 | 1.00E + 00 |
DRB1*11:02 | 0 | 113 | 113 | 0.28% | 1.00E + 00 | 1.00E + 00 |
DRB1*04:08 | 0 | 107 | 107 | 0.39% | 1.00E + 00 | 1.00E + 00 |
DRB1*15:01 | 2 | 103 | 105 | 13.50% | 1.00E + 00 | 1.00E + 00 |
DRB1*14:01 | 1 | 88 | 89 | 2.60% | 1.00E + 00 | 1.00E + 00 |
DRB1*15:02 | 0 | 55 | 55 | 0.72% | 1.00E + 00 | 1.00E + 00 |
DRB1*04:07 | 0 | 54 | 54 | 1.10% | 1.00E + 00 | 1.00E + 00 |
DRB1*04:03 | 1 | 49 | 50 | 0.79% | 1.00E + 00 | 1.00E + 00 |
DRB1*04:02 | 0 | 49 | 49 | 1.10% | 1.00E + 00 | 1.00E + 00 |