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Table 3 Significantly enriched GO Terms for the three vocabularies obtained via ClueGO (FDR <‚ÄČ0.05)

From: Dietary supplementation with olive mill wastewaters induces modifications on chicken jejunum epithelial cell transcriptome and modulates jejunum morphology

GO-ID GO-Term FDR Nr. Genes Associated Genes Found
GO:0006066 alcohol metabolic process 2,30E-04 11,00 [ABHD3, CHDH, CHPT1, CYP51A1, DHCR24, ENPP7, FDPS, HMGCS1, INSIG1, MSMO1, NSDHL]
GO:0016126 sterol biosynthetic process 2,70E-04 5,00 [CYP51A1, FDPS, HMGCS1, INSIG1, MSMO1]
GO:0000793 condensed chromosome 3,30E-04 8,00 [BRCA1, CENPW, MSH4, NDC80, NEK2, PLK1, SGOL1, SMC2]
GO:1901615 organic hydroxy compound metabolic process 3,40E-04 13,00 [ABHD3, ALDH9A1, BBOX1, CHDH, CHPT1, CYP51A1, DHCR24, ENPP7, FDPS, HMGCS1, INSIG1, MSMO1, NSDHL]
GO:0008610 lipid biosynthetic process 3,70E-04 14,00 [AGMO, BRCA1, CHPT1, CYP51A1, FDFT1, FDPS, GPAM, HMGCS1, INSIG1, MSMO1, NSDHL, PIGA, PLD1, TCF7L2]
GO:0016125 sterol metabolic process 3,80E-04 7,00 [CYP51A1, DHCR24, FDPS, HMGCS1, INSIG1, MSMO1, NSDHL]
GO:0000794 condensed nuclear chromosome 4,00E-04 6,00 [BRCA1, MSH4, NDC80, NEK2, PLK1, SGOL1]
GO:0008203 cholesterol metabolic process 6,20E-04 6,00 [CYP51A1, DHCR24, FDPS, HMGCS1, INSIG1, NSDHL]
GO:1902652 secondary alcohol metabolic process 6,90E-04 6,00 [CYP51A1, DHCR24, FDPS, HMGCS1, INSIG1, NSDHL]
GO:0006695 cholesterol biosynthetic process 7,20E-04 4,00 [CYP51A1, FDPS, HMGCS1, INSIG1]
GO:1902653 secondary alcohol biosynthetic process 7,20E-04 4,00 [CYP51A1, FDPS, HMGCS1, INSIG1]
GO:0006577 amino-acid betaine metabolic process 1,10E-03 3,00 [ALDH9A1, BBOX1, CHDH]
GO:0006631 fatty acid metabolic process 1,10E-03 9,00 [AACS, AGMO, BRCA1, ETFA, GPAM, HADHA, INSIG1, MSMO1, SLC27A4]
GO:0051297 centrosome organization 1,20E-03 6,00 [BRCA1, HAUS8, NEK2, NPM1, PLK1, SGOL1]
GO:0032787 monocarboxylic acid metabolic process 1,20E-03 12,00 [AACS, AGMO, ALDH9A1, BBOX1, BRCA1, ETFA, GPAM, HADHA, INSIG1, MSMO1, SLC27A4, VNN1]
GO:0098813 nuclear chromosome segregation 1,30E-03 8,00 [MSH4, NDC80, NEK2, NUSAP1, PLK1, SGOL1, SMC2, UBE2C]
GO:0007059 chromosome segregation 1,50E-03 9,00 [BRCA1, MSH4, NDC80, NEK2, NUSAP1, PLK1, SGOL1, SMC2, UBE2C]
GO:0000780 condensed nuclear chromosome, centromeric region 1,50E-03 3,00 [NDC80, PLK1, SGOL1]
GO:0031023 microtubule organizing center organization 1,50E-03 6,00 [BRCA1, HAUS8, NEK2, NPM1, PLK1, SGOL1]
GO:0046165 alcohol biosynthetic process 1,60E-03 6,00 [CHPT1, CYP51A1, FDPS, HMGCS1, INSIG1, MSMO1]
GO:0006576 cellular biogenic amine metabolic process 1,60E-03 5,00 [ABHD3, CHDH, CHPT1, ENPP7, SMOX]
GO:0045132 meiotic chromosome segregation 1,90E-03 4,00 [MSH4, PLK1, SGOL1, SMC2]
GO:0042439 ethanolamine-containing compound metabolic process 2,20E-03 4,00 [ABHD3, CHDH, CHPT1, ENPP7]
GO:1901617 organic hydroxy compound biosynthetic process 2,20E-03 7,00 [BBOX1, CHPT1, CYP51A1, FDPS, HMGCS1, INSIG1, MSMO1]
GO:0000070 mitotic sister chromatid segregation 2,30E-03 6,00 [NDC80, NEK2, NUSAP1, PLK1, SMC2, UBE2C]
GO:0097164 ammonium ion metabolic process 2,70E-03 6,00 [ABHD3, ALDH9A1, BBOX1, CHDH, CHPT1, ENPP7]
GO:0008608 attachment of spindle microtubules to kinetochore 2,80E-03 3,00 [NDC80, NEK2, SGOL1]
GO:0000779 condensed chromosome, centromeric region 3,10E-03 4,00 [CENPW, NDC80, PLK1, SGOL1]
GO:0045071 negative regulation of viral genome replication 3,10E-03 3,00 [EIF2AK2, OASL, RSAD2]
GO:0009308 amine metabolic process 4,00E-03 5,00 [ABHD3, CHDH, CHPT1, ENPP7, SMOX]
GO:0003725 double-stranded RNA binding 4,00E-03 4,00 [DHX58, EIF2AK2, OASL, TLR3]
GO:0008202 steroid metabolic process 4,00E-03 7,00 [CYP51A1, DHCR24, FDPS, HMGCS1, INSIG1, MSMO1, NSDHL]
GO:0044106 cellular amine metabolic process 4,10E-03 5,00 [ABHD3, CHDH, CHPT1, ENPP7, SMOX]
GO:0000281 mitotic cytokinesis 4,10E-03 3,00 [MITD1, NUSAP1, PLK1]
GO:0009615 response to virus 4,60E-03 8,00 [DDX60, DHX58, EIF2AK2, GPAM, IKBKE, OASL, RSAD2, TLR3]
GO:0000819 sister chromatid segregation 4,70E-03 6,00 [NDC80, NEK2, NUSAP1, PLK1, SMC2, UBE2C]
GO:0000776 kinetochore 4,90E-03 5,00 [CENPW, NDC80, NEK2, PLK1, SGOL1]
GO:1904030 negative regulation of cyclin-dependent protein kinase activity 7,70E-03 3,00 [NPM1, PLK1, UBE2C]
GO:0008654 phospholipid biosynthetic process 8,40E-03 5,00 [CHPT1, FDPS, GPAM, PIGA, PLD1]
GO:0061640 cytoskeleton-dependent cytokinesis 8,50E-03 3,00 [MITD1, NUSAP1, PLK1]
GO:0000777 condensed chromosome kinetochore 9,10E-03 3,00 [CENPW, NDC80, PLK1]
GO:0045840 positive regulation of mitotic nuclear division 9,10E-03 3,00 [NUSAP1, PLK1, UBE2C]
GO:0072330 monocarboxylic acid biosynthetic process 1,00E-02 5,00 [AGMO, BBOX1, BRCA1, INSIG1, MSMO1]
GO:0046486 glycerolipid metabolic process 1,20E-02 7,00 [ABHD3, CHPT1, GPAM, INSIG1, PIGA, PLD1, TCF7L2]
GO:0044242 cellular lipid catabolic process 1,30E-02 5,00 [ENPP7, ETFA, GALC, HADHA, SLC27A4]
GO:0098661 inorganic anion transmembrane transport 1,30E-02 4,00 [ANO6, LOC101748788, SLC20A1, SLC26A2]
GO:1903901 negative regulation of viral life cycle 1,40E-02 3,00 [EIF2AK2, OASL, RSAD2]
GO:0008081 phosphoric diester hydrolase activity 1,40E-02 4,00 [ENPP7, GDPD1, PDE9A, PLD1]
GO:0051785 positive regulation of nuclear division 1,40E-02 3,00 [NUSAP1, PLK1, UBE2C]
GO:0051607 defense response to virus 1,50E-02 6,00 [DDX60, DHX58, GPAM, OASL, RSAD2, TLR3]
GO:0006633 fatty acid biosynthetic process 1,50E-02 4,00 [AGMO, BRCA1, INSIG1, MSMO1]
GO:0015103 inorganic anion transmembrane transporter activity 1,50E-02 4,00 [ANO6, LOC101748788, SLC20A1, SLC26A2]
GO:0045069 regulation of viral genome replication 1,50E-02 3,00 [EIF2AK2, OASL, RSAD2]
GO:0000922 spindle pole 1,50E-02 4,00 [NEK2, NPM1, PLK1, SGOL1]
GO:0048806 genitalia development 1,60E-02 3,00 [DHCR24, KLHL10, TCF7L2]
GO:0048525 negative regulation of viral process 1,70E-02 3,00 [EIF2AK2, OASL, RSAD2]
GO:1902850 microtubule cytoskeleton organization involved in mitosis 1,80E-02 3,00 [NDC80, NEK2, PLK1]
GO:0000775 chromosome, centromeric region 1,90E-02 5,00 [CENPW, NDC80, NEK2, PLK1, SGOL1]
GO:0022626 cytosolic ribosome 2,10E-02 4,00 [RP11-849F2.7, RPL21, RPL9, RPS23]
GO:0043901 negative regulation of multi-organism process 2,10E-02 4,00 [DHX58, EIF2AK2, OASL, RSAD2]
GO:1901989 positive regulation of cell cycle phase transition 2,10E-02 3,00 [NPM1, PLK1, UBE2C]
GO:0006641 triglyceride metabolic process 2,10E-02 3,00 [GPAM, INSIG1, TCF7L2]
GO:0090068 positive regulation of cell cycle process 2,20E-02 5,00 [BRCA1, NPM1, NUSAP1, PLK1, UBE2C]
GO:0009062 fatty acid catabolic process 2,30E-02 3,00 [ETFA, HADHA, SLC27A4]
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2,30E-02 4,00 [CHDH, DHCR24, HADHA, NSDHL]
GO:0035725 sodium ion transmembrane transport 2,30E-02 4,00 [ANO6, CNKSR3, SLC20A1, STOML1]
GO:0019079 viral genome replication 2,30E-02 3,00 [EIF2AK2, OASL, RSAD2]
GO:0007126 meiotic nuclear division 2,40E-02 4,00 [MSH4, PLK1, SGOL1, SMC2]
GO:0022625 cytosolic large ribosomal subunit 2,60E-02 3,00 [RP11-849F2.7, RPL21, RPL9]
GO:0045017 glycerolipid biosynthetic process 2,60E-02 4,00 [CHPT1, PIGA, PLD1, TCF7L2]
GO:0006639 acylglycerol metabolic process 2,70E-02 3,00 [GPAM, INSIG1, TCF7L2]
GO:0045444 fat cell differentiation 2,80E-02 5,00 [FNDC5, INSIG1, PEX11A, SOCS1, TCF7L2]
GO:0015698 inorganic anion transport 2,80E-02 4,00 [ANO6, LOC101748788, SLC20A1, SLC26A2]
GO:0006638 neutral lipid metabolic process 2,80E-02 3,00 [GPAM, INSIG1, TCF7L2]
GO:0007051 spindle organization 2,80E-02 4,00 [HAUS8, NDC80, NEK2, PLK1]
GO:0007098 centrosome cycle 3,00E-02 3,00 [BRCA1, NEK2, NPM1]
GO:0005254 chloride channel activity 3,00E-02 3,00 [ANO6, LOC101748788, SLC26A2]
GO:1903046 meiotic cell cycle process 3,00E-02 4,00 [MSH4, PLK1, SGOL1, SMC2]
GO:0007052 mitotic spindle organization 3,30E-02 3,00 [NDC80, NEK2, PLK1]
GO:0051092 positive regulation of NF-kappaB transcription factor activity 3,30E-02 3,00 [EIF2AK2, NPM1, TLR3]
GO:0004386 helicase activity 3,40E-02 4,00 [DDX60, HELB, MOV10, PIF1]
GO:0072329 monocarboxylic acid catabolic process 3,40E-02 3,00 [ETFA, HADHA, SLC27A4]
GO:0004620 phospholipase activity 3,40E-02 3,00 [ABHD3, ENPP7, PLD1]
GO:0051983 regulation of chromosome segregation 3,40E-02 3,00 [NEK2, PLK1, UBE2C]
GO:0010565 regulation of cellular ketone metabolic process 3,50E-02 3,00 [BRCA1, INSIG1, TCF7L2]
GO:1902476 chloride transmembrane transport 3,60E-02 3,00 [ANO6, LOC101748788, SLC26A2]
GO:0051321 meiotic cell cycle 3,60E-02 4,00 [MSH4, PLK1, SGOL1, SMC2]
GO:0051225 spindle assembly 3,60E-02 3,00 [HAUS8, NEK2, PLK1]
GO:0005253 anion channel activity 3,70E-02 3,00 [ANO6, LOC101748788, SLC26A2]
GO:2001251 negative regulation of chromosome organization 3,70E-02 3,00 [BRCA1, PIF1, PLK1]
GO:0015297 antiporter activity 3,90E-02 3,00 [LOC101748788, SLC26A2, SLC7A4]
GO:0015108 chloride transmembrane transporter activity 3,90E-02 3,00 [ANO6, LOC101748788, SLC26A2]
GO:0050660 flavin adenine dinucleotide binding 3,90E-02 3,00 [CHDH, DHCR24, ETFA]
GO:0051053 negative regulation of DNA metabolic process 4,00E-02 3,00 [ENPP7, PIF1, POLQ]
GO:1904029 regulation of cyclin-dependent protein kinase activity 4,50E-02 3,00 [NPM1, PLK1, UBE2C]
GO:0008286 insulin receptor signaling pathway 4,80E-02 3,00 [IRS4, KL, SOCS1]
  1. GO-ID GO term accession number, GOTerm name of Gene Ontology Term, FDR (False Discovery Rate) after Benjamini-Hochberg correction, Nr. Genes number of input genes found per term, Associated Genes Found associated name of genes found per term