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Table 3 Tuberculosis disease characteristics associated with mixed infection. Nine individuals with mixed infections based on heterozygous sites but not with the Bayesian clustering method were excluded

From: Identifying mixed Mycobacterium tuberculosis infections from whole genome sequence data

Characteristic Mixed / Total % mixed P-value
Year
 1995–1999 46/539 8.5  
 2000–2004 82/662 12.4  
 2005–2009 44/506 8.7  
 2010–2014 14/247 5.7 0.009
Age group (years)
  < 15 2/34 5.9  
 15–29 61/586 10.4  
 30–44 87/866 10.1  
 45+ 36/468 7.7 0.4
Sex
 Female 94/995 9.5  
 Male 92/959 9.6 0.9
HIV status
 Negative 52/636 8.2  
 Positive 69/754 9.2  
 Positive on ART 10/120 8.3 0.8
 Unknown 55/444 12.4  
Previous TB
 No 173/1830 9.5  
 Yes 13/124 10.5 0.7
Lineage
 1 35/314 11.2  
 2 14/80 17.5  
 3 15/212 7.1  
 4 122/1343 9.1  
M. bovis 0/5 0.0 0.08
Type of TB
 Smear + 125/1462 8.6  
 Smear - 53/400 13.3  
 Extra-pulmonary 8/92 8.7 0.02
Outcome
 Completed 116/1275 9.1  
 Died 41/405 10.1  
 Lost/transferred 29/274 10.6 0.7
Isoniazid resistance
 Resistant 15/130 11.5  
 Sensitive 169/1757 9.3 0.5
Rifampicin resistance
 Resistant 2/17 11.8  
 Sensitive 182/1870 9.7 0.7
  1. P values from chi-square test except for associations with rifampicin resistance for which the Fisher exact test was used because of small numbers; ART Antiretroviral therapy