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Fig. 6 | BMC Genomics

Fig. 6

From: The inconsistent regulation of HOXC13 on different keratins and the regulation mechanism on HOXC13 in cashmere goat (Capra hircus)

Fig. 6

LEF1 and melatonin up-regulated the promoter activity of HOXC13. a LEF1 promoted the promoter activity of HOXC13. LEF1 overexpression vector together with HOXC13 p365-PGL3 basic vector were transfected into dermal papilla cells. LEF1 X1 and LEF X3 are two spliceosomes of LEF1. Truncated LEF1 (ΔLEF1) was used as a negative control. b Melatonin had a positive regulation on the promoter activity of HOXC13. Exogenous melatonin with concentration gradient was added into dermal papilla cells together with HOXC13 promoter-PGL 3 vector. The data was expressed as the mean ± 1 SE (n = 3). * P < 0.05, ** P < 0.01

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