From: Systematic evaluation of isoform function in literature reports of alternative splicing
Types of distinctness | Human genes | Mouse genes | |
---|---|---|---|
Distinct expression patterns | Cell-type-specific | AR, MADD | |
Developmental-stage-specific | CD44 | Myh10, Robo3 | |
Cellular localization | BIRC5, CSPP1, PRMT5, PML | Myh10, Rbfox1, Robo3, Sirt3 | |
Tissue-specific | MST1R | Calca, Rock2 | |
Other-condition-specific | BOK | ||
Biochemically distinct | Protein domain | CFLAR, DPF3, EIF4G1, TICAM1, TP63 | Lrp8 |
Dominant negative | BIRC5, HBS1L, KLF6, Nf1, PRMT5, STIM2, SUN1, TICAM | Enc1, Nf1, Robo3, Ryr3, Tp63 | |
Protein terminus change | BCAR1, BDNF, EIF4G2, IL1RAP, PGAM5 | Cacna1b, Mecp2, Oprm1, Pn4 | |
UTR Change | BDNF |