Fig. 3

RNA-Seq analysis of differentially expressed genes (DEGs) in tMCAO model conditions. There are RNA-Seq results in IR4.5 vs. SH4.5, IR24 vs. SH24, IR24 vs. IR4.5, SH24 vs. SH4.5. a Schematic comparison of the results obtained for the groups. b The numbers of up- and down-regulated DEGs are indicated by white and black bars, respectively. The numbers placed above the bars indicate the number of DEGs. c The numbers of DEGs overlapped in two pairwise comparisons: IR4.5 vs. SH4.5 and IR24 vs. SH24. d Diagrams showing DEGs that lie within the section of sets on the Venn diagrams (c). The numbers of up- and down-regulated DEGs are indicated by white and black bars, respectively. The numbers placed above the bars indicate the number of DEGs. Genes with a change in expression > 1.5-fold compared with the baseline value and with a Padj < 0.05 were selected for analysis