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Fig. 6 | BMC Genomics

Fig. 6

From: Genome-wide transcriptome analysis using RNA-Seq reveals a large number of differentially expressed genes in a transient MCAO rat model

Fig. 6

KEGG database analyses of the signaling pathway annotations for differentially expressed genes (DEGs). a Venn diagrams showing common and unique signaling pathways associated with DEGs in IR4.5 vs. SH4.5, IR24 vs. SH24, IR24 vs. IR4.5, SH24 vs. SH4.5. The numbers in the sectors indicate the number of signaling pathway annotations for DEGs. b, c, d The most significant signaling pathways and corresponding P-values adjusted using the Benjamini–Hochberg procedure, as well as the number of up- and down-regulated DEGs in IR4.5 vs. SH4.5 (b), IR24 vs. SH24 (c), IR24 vs. IR4.5 (d). Genes with a change in expression > 1.5-fold compared with the baseline value and with a P-value < 0.05 were selected for analysis

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