Comparative genome analysis reveals key genetic factors associated with probiotic property in Enterococcus faecium strains

Table 1 General Genome Features

Features	Probiotic		Non-Pathogenic		Pathogenic
Features	T110	17OM39	NRRLB-2354	64/3	DO	Aus0004	Aus0085	6E6	E39	ATCC 700221
Size (mb)	2.6	2.6	2.6	2.5	2.6	2.9	2.9	2.9	2.7	2.8
GC%	38.4	38.5	37.8	38.2	37.9	38.3	37.9	37.6	37.8	37.8
Genes	2639	2865	2771	2508	2795	2960	3214	3404	3043	3145
CDS	2502	2639	2658	2418	2703	2825	2938	3307	2907	2725
Pseudo Genes	54	148	47	32	32	70	181	73	44	326
rRNAs (5S, 16S, 23S)	6, 6, 6	6, 6,6	6, 6, 6	6, 6, 6	6, 6, 6	6, 6, 6	6, 6, 6	6, 6, 6	6, 6, 6	6, 6, 6
tRNAs	65	62	48	68	62	47	76	75	70	72
Plasmid	1	–	1	–	3	3	6	2	5	3
Accession code	NZ_CP006030.1	LWHF 00000000.1	NC_020207.1	NZ_CP012522.1	NC_017960.1	NC_017022.1	NC_021994.1	NZ_CP013994.1	NZ_CP011281.1	CP 014449.1
Source	probiotic	feces	cheese	feces	blood	blood	blood	feces	blood	feces
Country	Japan	India	–	Germany	USA	Australia	Australia	USA	USA	USA
Reference	Natarajan and Parani 2015	Ghattargi et al. 2018	Kopit et al. 2014	Bender et al. 2015	Lam et al. 2012	Qin et al. 2012	Qin et al. 2012	Geldart and Kaznessis 2017	Geldart and Kaznessis 2017	McKenney et al. 2016

ISSN: 1471-2164