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Table 1 Comparison of detected cytogenetic aberrations

From: Systematic evaluation of signal-to-noise ratio in variant detection from single cell genome multiple displacement amplification and exome sequencing

Analysis

dup(1q)

del(1p)

der(1)t(1;18) (p11;q11)

der(1;7) (p11;q22)

+i(5p)

+ 8

del(13)

dup(17)

del(19q)

Quentmeier & al.

+

+

+

+

+

+

24-color karyotyping

+

+

+

+

+

+

Exome sequencing

+a

+

+b

+c

+

+

+a

+

  1. a Gains were detected from 5 cells and up, whereas losses were detected down to single cells. b The translocation involves a copy-gain and is thus matched by whole exome sequencing allele frequency analysis. c Observed as gain