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Fig. 11 | BMC Genomics

Fig. 11

From: Transcriptional profiling of liver during the critical embryo-to-hatchling transition period in the chicken (Gallus gallus)

Fig. 11

The D1 vs. D9 contrast revealed two distinct gene networks centered on interaction among multiple lipogenic transcription factors. The gene network shown in Panel a was functionally annotated as “Lipid Metabolism”. Seven upstream regulators [THRSP, MID1 interacting protein 1 (MID1IP1 or THRSPL), SREBF2, cAMP responsive element modulator (CREM), Jun proto-oncogene, AP-1 transcription factor subunit (JUN), BTG anti-proliferation factor 2 (BTG2) and PLAG1 like zinc finger 1 (PLAGL1] and their direct target genes were mainly expressed at higher levels in liver of fed D9 hatchlings. The gene network in Panel b focusses on interactions of PPARG, which was expressed higher in liver of fully-fed D9 hatchlings, with four other transcription factors, three of which (NCOR1, NR0B1 and PPARGC1A) were more abundant in liver of fasted D1 hatchling chicks

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BMC Genomics

ISSN: 1471-2164

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