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Fig. 1 | BMC Genomics

Fig. 1

From: Comparison of RNA-seq and microarray platforms for splice event detection using a cross-platform algorithm

Fig. 1

EventPointer overview for junction arrays and RNA-Seq data. a The CEL or BAM files are the input data for each technology. The splicing graph for each gene is built using the array annotation files or directly using the sequenced reads. b Each node in the splicing graph is splitted into two nodes that correspond to the start and end positions in the genome respectively. EventPointer identifies events within each gene and annotates the type of event. In the figure, among the events in the gene, an exon cassette is highlighted. c Statistical significance of the events is computed. d Finally, the top-ranked events are validated using PCR and the results visualized in IGV

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