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Fig. 6 | BMC Genomics

Fig. 6

From: Environmental pH modulates transcriptomic responses in the fungus Fusarium sp. associated with KSHB Euwallacea sp. near fornicatus

Fig. 6

Schematic representation of a putative secondary metabolite genes cluster involved in synthesis of polyketides (PK) or nonribosomal peptides (NRP) which are coded in silenced heterochromatin. This inactive heterochromatin is converted to active euchromatin once LaeA protein interferes with associated methylases or deacetylases, allowing the expression of the genes cluster. a The expression profile of a putative LaeA protein of Fusarium sp. associated with KSBH at the distinct pH conditions analyzed is shown in the bar graph where transcripts levels are represented in transcripts per million (TPM). b Primary structure of Fusarium sp. associated with KSBH LaeA protein in which the methyltransferase domain and SAM binding site are represented by orange and red boxes, respectively). Amino acid comparison of LaeA proteins from F. verticillioides and Fusarium sp. associated with KSBH in which the conserved SAM binding sites are highlighted in red is also presented. Finally, panel (c), the expression profiles of each of the Fusarium sp. associated with KSBH nr-unigenes identified as homologs to polyketide synthases (PKS1 and FUB1) or nonribosomal peptide synthases (PES1 and NPS6) are shown

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