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Fig. 2 | BMC Genomics

Fig. 2

From: Transcriptional defects and reprogramming barriers in somatic cell nuclear reprogramming as revealed by single-embryo RNA sequencing

Fig. 2

Single-cell transcriptional profiles of in vivo embryos, NT embryos and donor cells. a PCA of all 60 samples revealing key relationships between groups. Smaller symbols represent each sample. Bigger symbols represent the average of samples from each group. b The number of genes displaying differential expression between adjacent developmental stages. c The number of genes exhibiting differential expression between different types of embryo at the same stage. d Heatmap of all 60 samples. Blue indicates lower expression and red indicates higher expression. The hierarchical clustering analysis of the samples is shown on top of the heatmap. The hierarchical clustering analysis of the genes is shown on the left. NTM_23 means the third sample of 2-cell NTM embryos. CC_1 means the first sample of cumulus cells, etc.

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