Fig. 3
a Differential expression of circadian rhythm genes between uninfected and Saprolegnia-infected Oreochromis niloticus. Positive (green) and negative (red) log2 fold changes indicate higher and lower expression in infected fish respectively. Zero change (white) indicates no significant difference in expression. b Network view of G9 gill module (circadian regulation of gene expression) hub genes. Nodes are labelled with official gene symbols when available. Edge line width represents connection strength (weight); thicker lines denote stronger connections. Node size is proportional to number connections. Node colour represents the log2 fold change between control and infected fish at 48 h post-exposure. Node borders represent differential gene expression results. Grey = nonsignificant; red = decreased expression in the infected; green = increased expression in the infected