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Fig. 2 | BMC Genomics

Fig. 2

From: Transcriptional profiling of embryos lacking the lipoprotein receptor SR-B1 reveals a regulatory circuit governing a neurodevelopmental or metabolic decision during neural tube closure

Fig. 2

Identification of candidate genes infuencing the phenotype of KO-NTD embryos. a. Genes involved in specific biological processes with differential expression are shown in Venn diagrams. b. Heatmap showing relative expression levels of the genes highlighted in the center of the Venn diagrams, based on the RNA-Seq data. The scale shows logarithmic fold change from the grand mean. c. rtPCR analysis of mRNA levels of the genes shown in (a) in embryos from dams fed control chow or a vitamin E-supplemented diet. N = 3 per group. ND: not detected. *p < 0.05, ***p < 0.001; Pair-Wise Fixed Reallocation Randomisation Test

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BMC Genomics

ISSN: 1471-2164

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