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Fig. 4 | BMC Genomics

Fig. 4

From: Transcriptional profiling of embryos lacking the lipoprotein receptor SR-B1 reveals a regulatory circuit governing a neurodevelopmental or metabolic decision during neural tube closure

Fig. 4

Shared transcriptional regulation of NTD-related and lipid metabolism genes. a. Shared transcription factors in the gene regulatory subnetworks of Apoa1, Apob, Apoe, and Pax3. b. Regulatory relationships connecting members of the regulatory circuit and the genes of interest through the shortest paths. c. Pearson correlation coefficients of mRNA levels of the genes of interest within each individual embryo assayed (N = 15). Colored cells indicate statistically significant correlations (p < 0.05). Green cells show positive correlation, while red cells have negative correlations

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