Fig. 5
From: Context-specific interactions in literature-curated protein interaction databases
Using technique-specific gold standard subsets increases interactome size and/or quality. a The size of interactomes produced by co-elution gold standard subsets of varying stringency (solid) or randomly selected subsets of the same size as the co-elution specific subsets (dashed, 95% CI). Interactomes have 50% precision. b 75% precision. c 90% precision. d Precision-recall curve for the interactome predicted using the entire gold standard set of interactions. e Precision-recall curve predicted using the gold standard complexes that satisfied the 10− 2 threshold. f 10− 6 threshold. g 10− 10 threshold. Precision-recall curves using random subsets of the same size are shown in red (95% CI)