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Table 2 Top 5 GO and KEGG terms of each transgenic tissue via modulatory enrichment with GeneCodis

From: RNA-Seq analysis of differentially expressed genes relevant to innate and adaptive immunity in cecropin P1 transgenic rainbow trout (Oncorhynchus mykiss)

Biological terms

Genes (I/R)1

P-value2

Identifier

Spleen

 Innate immune response (BP)

7/12

2.68E-04

GO: 0045087

 Immune response (BP)

19/86

2.87E-04

GO: 0006955

 Cell adhesion (BP)

29/198

1.98E-03

GO: 0007155

 Negative regulation of cell proliferation (BP)

20/128

7.18E-03

GO: 0008285

 Cytokine-mediated signaling pathway (BP)

13/41

5.83E-04

GO: 0019221

Kidney

 Inflammatory response (BP)

6/8

1.55E-05

GO: 0006954

 Regulation of immune response (BP)

8/21

8.65E-05

GO: 0050776

 Cell adhesion (BP)

6/23

1.97E-03

GO: 0007155

 PPAR signaling pathway

7/23

5.63E-04

KEGG: 03320

 Hematopoietic cell lineage

5/10

5.99E-04

KEGG: 04640

Liver

 Cellular lipid metabolic process (BP)

3/11

5.38E-03

GO: 0044255

 PPAR signaling pathway

KEGG: 03320

 Immune response (BP)

7/86

6.06E-03

GO: 0006955

 Chemokine signaling pathway

3/7

3.00E-03

KEGG: 04062

 Cholesterol homeostasis (BP)

4/20

3.98E-03

GO: 0042632

 Starch and sucrose metabolism

4/25

4.86E-03

KEGG: 00500

  1. 1I/R stand for numbers of annotated genes in the input list divided by numbers of annotated genes in the reference list; 2The P-values were calculated by hypergeometric analysis and adjusted by false detection rate (FDR) for multiple corrections