RNA-Seq analysis of differentially expressed genes relevant to innate and adaptive immunity in cecropin P1 transgenic rainbow trout (Oncorhynchus mykiss)

Table 3 Summary of tissue specific pathway analyses of cecropin P1 transgenic rainbow trout via KEGG database

Pathways	DEGs (I/R)^a	P-Values	KEGG ID^b
Spleen
Chemokine and Cytokine JAK-STAT	45/562	1.52E-07	KO04060
	40/913	6.69E-03	KO04062
	32/493	4.63E-04	KO04630
Complement and Coagulation cascade	26/325	6.16E-05	KO04610
Toll-like receptor	29/435	5.47E-05	KO04620
Antigen processing and presentation	32/290	6.95E-09	KO04612
Leukocyte trans-epithelial migration	51/735	1.79E-06	KO04670
Fc ε RI signaling and γ R-mediated phagocytosis	29/458	1.22E-03	KO04664
Fc ε RI signaling and γ R-mediated phagocytosis	44/809	1.86E-03	KO04666
Liver
PPAR signaling	22/325	1.62E-10	KO03320
Phagosome	31/806	3.43E-08	KO04145
Complement and Coagulation cascade	27/325	9.74E-15	KO04610
Fatty acid biosynthesis	6/33	2.88E-06	KO00061
Kidney
PPAR signaling	39/325	6.13E-16	KO03320
Hematopoietic cell lineage	40/445	3.65E-12	KO04640
Leukocyte trans-epithelial migration	28/735	1.82E-02	KO04670

^aI/R stands for mapped DEGs in each tissue divided by total annotated genes in the contributing KEGG pathways. ^bKEGG ID indicates the acknowledgements to the corresponding pathways were modified and sprayed expression data from the original sources

ISSN: 1471-2164