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Fig. 2 | BMC Genomics

Fig. 2

From: Profiling the miRNA-mRNA-lncRNA interaction network in MSC osteoblast differentiation induced by (+)-cholesten-3-one

Fig. 2

Candidate mRNA predictions and CNC network construction during CN-induced MSC osteoblast differentiation. a In total, 443 mRNAs were predicted via mRBase targets based on the miRNA and lncRNA microarray. Seven mRNAs (Vdr, Mgp, Fst, Cd38, Nln, Rfc3 and Car9) were selected for validation via qRT-PCR, and the results were consistent with the predicted target genes. b CNC networks during the CN-induced osteoblast differentiation of MSCs. The dots represent mRNAs, the dots in circles represent lncRNAs, and the squares represent miRNAs. All the red dots represent upregulation, and all the blue dots represents downregulation. P < 0.05, compared to the control group

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