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Table 2 Fusion discoveries in the spike-in dataset. The results for TopHat-Fusion, SOAPfuse and JAFFA for sample SRR1659964 are collected from a recent study [9]

From: A fast detection of fusion genes from paired-end RNA-seq data

 

One sample(SRR1659964)

20 samples

 

TP

Total

Precision

Recall

F1

P-value

TP

Other

P-value

FusionMap

7

26

0.27

0.78

0.40

0.78

142/180

283

0.04

TRUP

4

9

0.44

0.44

0.44

1

80/180

63

0.15

JAFFA

5

13

0.39

0.56

0.46

1

138/180

114

0.12

SOAPfuse

4

13

0.31

0.44

0.36

1

NA

NA

NA

TopHat-Fusion

1

6

0.17

0.11

0.13

0.66

133/180

925

1.6e-22

FuSeq

9

25

0.36

1

0.53

-

179/180

228

-

  1. TP= true positive fusion genes, Other= unvalidated fusion genes, Total= total discovered fusion-gene candidates, P-value = two-sided p-value of Fisher’s exact test of the difference in precision between FuSeq vs each of the other methods