Fig. 1From: Distinct esophageal adenocarcinoma molecular subtype has subtype-specific gene expression and mutation patternsIdentification of two molecular subtypes of esophageal adenocarcinoma. a Area under empirical cumulative distribution plots (k = 2 to k = 12) determined the two optimal molecular subtypes of EAC. (k denotes the number of clusters). b Consensus matrix displaying the two robust subgroups of EAC were defined by gene expression. c Significance analysis of subtype classifications in each dataset was determined by SigClust. d Silhouette analysis of EAC samples based on the assignments from Consensus Clustering. e Subclass association (SA) matrix of molecular subtypes between three cohorts. The rainbow bar indicates the FDR-corrected p valueBack to article page