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Table 1 Molecular, cellular and physiological categories significantly over-represented among the differentially expressed genes

From: RNA-seq of muscle from pigs divergent in feed efficiency and product quality identifies differences in immune response, growth, and macronutrient and connective tissue metabolism

Category

B-H p-value range*

Z-score rangea

Haematological System Development & Function

1.72E-11 – 5.00E-03

-2.13 – 3.52b

Lymphoid Tissue Structure & Development

1.72E-11 – 5.00E-03

-0.65 – 2.94b

Tissue Morphology

1.72E-11 – 5.16E-03

-2.13 – 2.87b

Cellular Movement

1.72E-11 – 5.74E-03

-0.36 – 3.52b

Immune Cell Trafficking

6.54E-11 – 5.74E-03

0.58 – 3.52b

Cellular Function & Maintenance

6.54E-11 – 4.56E-03

-0.06 – 2.83b

Cellular Development

1.29E-10 – 5.00E-03

-0.65 – 1.64

Cellular Growth & Proliferation

1.29E-10 – 5.00E-03

-0.65 – 1.73

Cell-To-Cell Signalling & Interaction

2.21E-09 – 5.74E-03

0.12 – 3.19b

Protein Synthesis

6.50E-09 – 2.32E-03

0.24 – 1.18

Humoral Immune Response

9.96E-09 – 3.58E-03

-0.57 – 1.89

Cellular Compromise

1.14E-08 – 2.80E-03

-1.51 – 2.20b

Cell-mediated Immune Response

1.79E-07 – 5.74E-03

0.58 – 2.94b

Free Radical Scavenging

2.33E-07 – 8.89E-07

1.13

Cell Death & Survival

2.42E-06 – 4.57E-03

-2.27 – 2.20b

Tissue Development

3.60E-06 – 4.56E-03

0.78 – 2.30b

Embryonic Development

5.77E-06 – 3.53E-03

0.54 – 1.50

Haematopoiesis

5.77E-06 – 1.11E-03

0.78 – 1.77

Organ Development

5.77E-06 – 3.94E-03

-0.66 – 1.50

Organismal Development

5.77E-06 – 4.95E-03

0.72 – 1.64

Cell Morphology

1.39E-05 – 4.95E-03

-0.08 – 2.09b

Lipid Metabolism

1.48E-05 – 1.19E-03

-1.23 – 0.60

Small Molecule Biochemistry

1.48E-05 – 5.74E-03

-1.23 – 0.60

Organ Morphology

1.70E-05 – 4.95E-03

1.06 – 1.77

Molecular Transport

1.97E-05 – 1.81E-03

-0.01 – 2.89b

Cardiovascular System Development & Function

2.63E-05 – 4.95E-03

-0.95 – 2.12b

Digestive System Development & Function

6.90E-05 – 5.38E-03

-0.66

Organismal Survival

8.09E-05 – 8.09E-05

-0.04

Cell Signalling

1.05E-04 – 1.81E-03

0.12 – 3.19b

Vitamin & Mineral Metabolism

1.05E-04 – 1.81E-03

2.36 – 2.89b

Cell Cycle

5.91E-04 – 3.94E-03

-0.49 – -1.98

Gene Expression

5.91E-04 – 3.53E-03

-1.98 – -0.49

Cellular Assembly & Organization

7.30E-04 – 5.74E-03

0.33 – 1.89

Renal & Urological System Development & Function

1.74E-03 – 3.94E-03

-0.15 – 0.76

Carbohydrate Metabolism

2.09E-03 – 2.09E-03

NA

Amino Acid Metabolism

2.74E-03 – 5.74E-03

NA

Hepatic System Development & Function

3.20E-03 – 3.20E-03

-0.66

Skeletal & Muscular System Development & Function

3.54E-03 – 3.54E-03

NA

Nervous System Development & Function

4.63E-0 – 4.63E-03

NA

  1. *Range of B-H multiple testing correction p-values of enriched functions within the category; arange of z-scores for sub-categories contained within a particular category; bannotations with a z-score > 2 and z-score < -2 were considered significantly activated and inhibited in high-FE pigs, respectively; NA: no activity pattern available