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Table 4 Fold enrichment and the percentage of cases where the effect of an allele is in the same direction across different analyses and tissues

From: Comparing allele specific expression and local expression quantitative trait loci and the influence of gene expression on complex trait variation in cattle

Analysis Tissue ASE eQTL
Angus muscle Angus liver Holstein liver Holstein WBC Angus muscle Angus liver Holstein liver Holstein WBC
ASE Angus muscle   34.82 8.78 3.09 5.89 4.02 9.75 2.00
Angus liver 100%   11.79 0.09 1.70 11.94 5.34 1.79
Holstein liver 100% 100%   27.43 1.89 7.80 12.02 0.87
Holstein WBC 100% 100% 100%   3.72 2.10 8.49 12.23
eQTL Angus muscle 98% 92% 62% 82%   12.28 7.35 10.84
Angus liver 100% 98% 99% 61% 94%   20.35 6.00
Holstein liver 100% 95% 97% 64% 97% 99%   20.36
Holstein WBC 91% 100% 62% 87% 96% 99% 100%  
  1. The fold enrichment (upper triangle) and the percentage of cases where the effect of an allele is in the same direction (lower triangle) in paired comparisons among ASE and eQTL analyses show that the overlap between significant SNPs (p < 0.001) is more than expected by chance and in majority of cases the same allele is associated with higher tSNP count or gene expression