Skip to main content
Fig. 3 | BMC Genomics

Fig. 3

From: Combined genetic influence of the nicotinic receptor gene cluster CHRNA5/A3/B4 on nicotine dependence

Fig. 3

Association of nicotine dependence with rs16969968 allele alone (G > A) and haplotype and diplotype comprised of rs880395 (G > A), rs16969968 (G > A), rs1948 (G > A) and rs4887074 (C > G), reported as odds ratio with 95% confidence intervals. For haplotype analysis, base allele of rs16969968 and haplotype is G and GGGG respectively. For diplotype analysis, bases are G-G of rs16969968 and AGAC-GGGG for diplotypes. Color represents different allele (or diplotypes) of rs16969968: blue; G (haplotype) or G-G (diplotype), green; G-A and red; A (haplotype) or A-A (diplotype) (*** p < .0001, **p < .01,*p < .05, adjusted p-value for multiple corrections). The number next to the genotype/ haplotype/ diplotype represents the frequency (%)

Back to article page