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Table 2 Pairwise LD of the lead SNPs in European population from 1000 genomes project

From: Combined genetic influence of the nicotinic receptor gene cluster CHRNA5/A3/B4 on nicotine dependence

 

rs880395

rs16969968

rs1948

rs4887074

rs6495308

rs880395

1

0.98 (0.33)

0.83 (0.54)

0.44 (0.04)

0.77 (0.11)

rs16969968

 

1

0.99 (0.27)

0.41 (0.03)

1 (0.18)

rs1948

  

1

0.52 (0.04)

0.92 (0.13)

rs4887074

   

1

0.42 (0.18)

rs6495308

    

1

  1. D’(R2); rs880395 (G > A, CHRNA5 enhancer, MAF = 0.38), rs16969968 (G > A, CHRNA5 nsSNP, MAF = 0.37), rs1948 (G > A, CHRNA3 enhancer, MAF = 0.32) and rs4887074 (C > G, candidate CHRNB4 repressor, MAF = 0.24) and rs6495308 (T > C, MAF =0.24)
  2. MAF Minor Allele Frequency
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BMC Genomics

ISSN: 1471-2164

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